[Multilocular cystic renal cell carcinoma]

Multilocular cystic renal cell carcinoma is an uncommon variant recently described of renal cell carcinoma. Analyze clinicopathological features, imaging findings and prognosis and therapeutic options of this tumor. The authors reported two cases of multilocular cystic renal cell carcinoma arising in 68 and 39 year old men. They were admitted with pain in the lumbar region and/or haematuria. The imaging findings were a renal neoplasm with cystic and solid areas. The pathologic findings confirm the diagnosis of multilocular cystic renal cell carcinoma. Multilocular cystic renal cell carcinoma, usually identified at earlier stages, had slower growth rate and was therefore associated with a better prognosis and longer survival than conventionnal renal cell carcinoma

Study of the ploidy and cellular cycle of hidra-denomas and hidradenocarcinomas: a series of 13 cases

To study by flow cytometry [FCM] the ploidy and the cellular cycle of nodular hidradenoma [NH] and hidradenocarcinoma [HC] and to assess the prognostic utility of this technique in such tumors. We studied retrospectively 2 HC and 11 NH one of which was considered as an atypical NH. Monoparametric study by FCM was realized on paraffin-embedded material. The extracted cells were marked by Propidium's lodure and cellular cycle was analyzed by the software Mod-Fit LT. Our study showed eleven 100% diploid profiles, 10 of which had low S-phase varying between 2 and 12%. All of these 11 tumors were NH. S-phase was high [23,79%] in a single case that corresponded to the atypical NH. Two tumors showed aneuploid profiles; these corresponded to the 2 HC. The results of the cytometrie study suit perfectly to those of the histopathologic examination. FCM could so help to establish the prognosis of these tumors. But further studies are necessary to determine the value of this technique